Hydrolysis resistant sialic acid derivatives and methods for their use

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United States of America Patent

PATENT NO 10023601
SERIAL NO

15119622

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Abstract

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This invention provides compound having a structure of Formulas: Furthermore, methods and uses of such compounds for covalently bonding to a sugar acceptor, to form modified protein therapeutics having reduced enzymatic hydrolysis, improved biological stability or an improved pharmacokinetic property.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF BRITISH COLUMBIAVANCOUVER BRITISH COLUMBIA V6T 1Z3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baumann, Lars Vancouver, CA 6 0
Morley, Thomas J New Haven, US 9 34
Withers, Stephen G Vancouver, CA 20 97

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