Sulfur(VI) fluoride compounds and methods for the preparation thereof

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United States of America Patent

PATENT NO 10117840
APP PUB NO 20170196985A1
SERIAL NO

15316742

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Abstract

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This application describes a compound represented by Formula (I): (I) wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X1 is a covalent bond or —CH2CH2—, X2 is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.

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Patent Owner(s)

Patent OwnerAddress
THE SCRIPPS RESEARCH INSTITUTE10550 NORTH TORREY PINES ROAD MAIL DROP TPC-8 LA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Wentao Walnut Creek, US 20 228
Dong, Jiajia Shanghai, CN 22 59
Kelly, Jeffery W La Jolla, US 28 206
Sharpless, K Barry La Jolla, US 51 895

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