Compositions and methods relating to salts of specialized pro-resolving mediators
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United States of America Patent
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Nov 20, 2018
Grant Date -
Jul 19, 2018
app pub date -
Jun 2, 2017
filing date -
Jun 3, 2016
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Abstract
The present invention relates to compounds which are salts of specialized pro-resolving mediators (referred to herein as “SPMs”) which include lipoxins, resolvins, protectins, and their aspirin-triggered counterparts. The SPM salts described here contain at least one or two SPM molecules ionically bound to at least one basic function that is provided by a scaffold moiety as described herein, compositions containing same, and methods of using same in the treatment of various diseases and disorders characterized by chronic or excessive inflammation, or both.
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