Composite column for use in high pressure liquid chromatography
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United States of America Patent
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Nov 20, 2018
Grant Date -
Dec 21, 2017
app pub date -
Jun 16, 2017
filing date -
Jun 16, 2016
priority date (Note) -
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status (Latency Note)
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Abstract
A multi-walled tube that is useful as an analytical column in which chemical mixtures can be separated into their individual components is described. In order to be acceptable as an analytical column, the inner surface of the multi-walled tube must support effective separation, but not react chemically with or contaminate the solvent or the analyte (sample to be separated). Grade 316 stainless steel is typically preferred for this purpose. Moreover, the inner diameter (ID) surface of the multi-walled column is preferably very smooth (less than 10 micro inch Ra) with no interruptions in the surface such as scratches, pits, or asperities. However, since the column is designed to be attached to chromatographic equipment using standard size connection features, the size of standard fittings define the outer diameter (OD) of the column.
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