Method for screening new drug candidate inhibiting target protein-protein interaction for development of first-in-class drug
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United States of America Patent
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Nov 20, 2018
Grant Date -
May 24, 2012
app pub date -
May 28, 2010
filing date -
May 28, 2009
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Abstract
The present invention relates to a method for screening a substance inhibiting protein-protein interactions, and more particularly to a method for screening a substance inhibiting protein-protein interactions, the method comprising using a protein chip having immobilized thereon spots comprising a mixture of a sol-gel material and a protein. According to the invention, a protein chip can be easily manufactured in a 96-well plate using a sol-gel material, whereby an inhibitor that inhibits protein-protein interactions can be easily screened from a library of natural substances.
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