Personalized myeloma detection

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United States of America Patent

PATENT NO 10175242
APP PUB NO 20160370372A1
SERIAL NO

15122269

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein is a personalized method for monitoring a condition or disorder associated with antibody production in a subject. The method can involve treating a biological sample comprising immunoglobulin from the subject to enzymatically cleave a target immunoglobulin associated with the PCD into one or more variable domain peptide fragments of the target immunoglobulin, and then measuring the one or more variable domain peptide fragments in the sample by quantitative mass spectrometry to quantify the amount of the target immunoglobulin in the sample.

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Patent Owner(s)

Patent OwnerAddress
H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC12902 MAGNOLIA DRIVE TAMPA FL 33612

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koomen, John Matthew Tampa, US 6 33

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