Antibody like protein

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United States of America Patent

PATENT NO 10370776
APP PUB NO 20160090400A1
SERIAL NO

14497320

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Abstract

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A general method and recombinant nucleic acid sequences, by means which the method selects a recombinant protein containing an FHA domain for binding a target molecule from a library proteins with a high-throughput method of creating protein variations within the FHA domain in non-conserved or non-structural sequences of the FHA scaffold, and the library may also be in the form of a phagemid or phage library wherein the ALP nucleic acid sequence is inserted into a vector capable of allowing the vector and expressed ALP protein from being virally packaged, and the recombinant nucleic acid sequences which are randomly mutated at varying non-conserved or non-structural FHA domain sequences.

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Patent Owner(s)

  • IDEA ORCHARD, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Longo, Michael Whittier, US 35 216
Perera, Rajika Cambridge, GB 4 2

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