FXR (NR1H4) binding and activity modulating compounds

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United States of America Patent

PATENT NO 10485795
APP PUB NO 20190142814A1
SERIAL NO

16248178

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Abstract

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The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

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Patent Owner(s)

Patent OwnerAddress
GILEAD SCIENCES INC333 LAKESIDE DRIVE FOSTER CITY CA 94404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinzel, Olaf Heidelberg, DE 37 369
Kremoser, Claus Heidelberg, DE 22 522
Steeneck, Christoph Dossenheim, DE 36 314

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