Method to produce chemical pattern in micro-fluidic structure
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United States of America Patent
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Nov 26, 2019
Grant Date -
Nov 16, 2017
app pub date -
May 23, 2017
filing date -
Sep 27, 2013
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The present disclosure provides flow cells and methods of fabricating flow cells. The method includes combining three portions: a first substrate, a second substrate, and microfluidic channels between the first substrate and the second substrate having walls of a photoresist dry film. Through-holes for inlet and outlet are formed in the first substrate or the second substrate. Patterned capture sites are stamped on the first substrate and the second substrate by a nanoimprint lithography process. In other embodiments, parts of the patterned capture sites are selectively attached to a surface chemistry pattern formed of silicon oxide islands each disposed on an outcrop of a soft bottom layer.
First Claim
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International Classification(s)
- A61J:CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMA....
- B43M:BUREAU ACCESSORIES NOT OTHERWISE PROVIDED FOR
- B82Y:SPECIFIC USES OR APPLICATIONS OF NANO-STRUCTURES; ....
- B06B:GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS I....
- B01L:CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENE....
- G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....
- B32B:LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA....
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