Method of preparing substituted bicyclo[1.1.1] pentanes

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United States of America

PATENT NO 10513483
SERIAL NO

16085163

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Abstract

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A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.

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Patent Owner(s)

Patent OwnerAddress
SPIROCHEM AG4058 BASEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fessard, Thomas Küsnacht, CH 6 27
Jimenez-Teja, Daniel Zurich, CH 1 3
Salomé, Christophe Herrlisheim près Colmar, FR 3 7
Suzuki, Yoshikazu Glattbrugg, CH 119 536

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