Silicone hydrogel lens with a crosslinked hydrophilic coating

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United States of America

PATENT NO 10563090
APP PUB NO 20190309188A1
SERIAL NO

16397255

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Abstract

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The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.

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Patent Owner(s)

Patent OwnerAddress
ALCON INCRUE LOUIS-D'AFFRY 6 FRIBOURG 1701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kolluru, Chandana Suwanee, US 11 117
Medina, Arturo Norberto Duluth, US 20 439
Nelson, Jared Buford, US 22 238
Pruitt, John Dallas Suwanee, US 52 595
Qian, Xinming Johns Creek, US 25 283
Qiu, Yongxing Suwanee, US 76 1633
Samuel, Newton T Suwanee, US 16 154
Winterton, Lynn Cook Keller, US 75 3174
Wu, Daqing Suwanee, US 48 394

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