infections

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 10577431
APP PUB NO 20190270827A1
SERIAL NO

16160880

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are monoclonal antibodies or binding portion thereof that bind specifically to a Staphylococcus spp. autolysin N-acetylmuramoyl-L-alanine amidase catalytic domain and/or cell wall binding domain, as well as pharmaceutical compositions containing the same. Cell lines expressing the monoclonal antibodies, including hybridomas, are also disclosed. Methods of using the monoclonal antibodies for installation of orthopedic implants, grafts or medical devices, treating or preventing a Staphylococcus infection, and treating osteomyelitis are described, as are diagnostic methods for the detection of Staphylococcus in a sample.

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Patent Owner(s)

  • UNIVERSITY OF ROCHESTER

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bello-Irizarry, Sheila Rochester, US 1 0
Brodell, James Rochester, US 1 0
Daiss, John L Rochester, US 21 391
Schwarz, Edward Rochester, US 14 818
Varrone, John J Rochester, US 2 0

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