Detecting target molecules in a sample

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United States of America Patent

PATENT NO 10670589
APP PUB NO 20180074047A1
SERIAL NO

15710887

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Abstract

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The invention relates to detection the presence of a target molecule in a sample, wherein the sample is contacted with a substrate, the substrate subsequently being washed in a wash step. In particular, the invention relates to a method of detecting the presence of a target molecule in a sample, the method comprising: (a) contacting the sample (37) with a substrate having immobilized thereon probe molecules that specifically binds to the target molecule; (b) washing the substrate (38) in a wash step by a wash fluid in order to remove or dilute unbound target molecules; (c) detect the presence of resultant binding complexes (39) on the substrate to determine whether the target molecule is present in the sample—The wash fluid being substantially refractive index matched to the substrate.

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Patent Owner(s)

Patent OwnerAddress
KONINKLIJKE PHILIPS N VHIGH TECH CAMPUS 52 EINDHOVEN 5656 AG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klunder, Derk Jan Wilfred Geldrop, NL 73 760
Stapert, Hendrik Roelof Rosmalen, NL 56 485
Van, Herpen Maarten Marinus Johannes Wilhelmus Heesch, NL 136 1028

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