Methods and kits for theranostic applications
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United States of America Patent
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Jul 7, 2020
Grant Date -
Jan 25, 2018
app pub date -
Dec 2, 2015
filing date -
Dec 2, 2014
priority date (Note) -
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status (Latency Note)
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Abstract
The present disclosure is directed to methods and kits for identifying, enriching, and evaluating templated assembly reactants. Some embodiments disclose methods for identifying templated assembly targets by synthesizing templated assembly reactants, hybridizing the templated assembly reactants to target nucleic acids, performing a templated assembly reaction, and identifying the target nucleic acids that hybridized to the templated assembly reactants. Libraries of templated assembly reactants, a kit for identifying templated assembly targets, and a pair of templated assembly targets enriched from a library of chemically-ligated oligonucleotides spatially elicited (CLOSE) products are also disclosed.
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