Methods of identifying and treating poor-prognosis cancers

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United States of America Patent

PATENT NO 10745701
APP PUB NO 20190292548A1
SERIAL NO

16230098

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Abstract

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The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. Embodiments of the present invention provide an objective means of prognostication regarding the long-term outcome of an incident of cancer, breast cancer in particular. Therapeutic modalities include immunotherapy and anti-sense therapy. Prognosis is determined by measuring the number of copies of the metadherin gene in the patient's cells.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF PRINCETON UNIVERSITY619 ALEXANDER ROAD SUITE 102 PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hu, Guohong Piscataway, US 30 170
Kang, Yibin Princeton, US 18 35

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