Isolating traffic-enhancing mutants of drug delivery protein

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United States of America Patent

PATENT NO 10752893
APP PUB NO 20180298376A1
SERIAL NO

16017866

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Abstract

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The invention relates to methods for isolating traffic-enhancing mutants of drug delivery proteins. In one embodiment, the invention provides a carrier for delivering a therapeutic agent to an organelle, comprising a polypeptide encoded by a mutant penton base gene. In another embodiment, the invention provides a method of enhancing trafficking to a cell by administering a composition comprising a penton base (PB) protein with one or more mutations that enhance cellular entry.

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Patent Owner(s)

Patent OwnerAddress
CEDARS-SINAI MEDICAL CENTER8700 BEVERLY BOULEVARD LOS ANGELES CA 90048

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Medina-Kauwe, Lali K Porter Ranch, US 16 107

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