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Abstract

This application describes a compound represented by Formula (I):

description='In-line Formulae' end='lead'YZX¹—S(O)(X²)F)_m]_n  (I)description='In-line Formulae' end='tail'

wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X¹ is a covalent bond or —CH₂CH₂—, X² is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.

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First Claim