Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors

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United States of America Patent

PATENT NO 10919913
APP PUB NO 20190169209A1
SERIAL NO

16272482

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Abstract

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The present invention encompasses compounds of formula (I) wherein the groups R1 to R7, A, V, W, X, Y, n, r and q are defined in claim 1, their use as inhibitors of MDM2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.

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Patent Owner(s)

  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Broeker, Joachim Moedling, AT 15 45
Gille, Annika Ulm, DE 11 34
Gollner, Andreas Vienna, AT 27 105
Henry, Manuel Schemmerhofen, DE 16 68
Kerres, Nina Vienna, AT 9 39
Ramharter, Juergen Vienna, AT 24 73
Weinstabl, Harald Vienna, AT 14 62

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