Methods for synthesizing nucleotide analogues with disulfide linkers

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United States of America Patent

PATENT NO 11117921
SERIAL NO

16423466

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Abstract

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The present invention provides methods, compositions, mixtures and kits utilizing deoxynucleoside triphosphates comprising a 3′-O position capped by a group comprising methylenedisulfide as a cleavable protecting group and a detectable label reversibly connected to the nucleobase of said deoxynucleoside. Such compounds provide new possibilities for future sequencing technologies, including but not limited to Sequencing by Synthesis.

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Patent Owner(s)

Patent OwnerAddress
ISOPLEXIS CORPORATION35 NORTH EAST INDUSTRIAL ROAD BRANFORD CT 06405

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Korboukh, Ilia Needham, US 8 70
Marma, Mong Sano Natick, US 14 124
Olejnik, Jerzy Brookline, US 108 1475

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