Method for mass humanization of non-human antibodies

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United States of America Patent

PATENT NO 11124581
APP PUB NO 20190263936A1
SERIAL NO

16156740

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Abstract

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The present invention relates to a method for producing a population of nucleic acids encoding at least one protein comprising at least one immunoglobulin variable domain having a non-human-derived CDR3 amino acid sequence embedded in essentially human framework sequences, as well as to a population of nucleic acids and a population of proteins relates thereto and uses thereof.

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Patent Owner(s)

  • CHARLES RIVER LABORATORIES INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Glanville, Jacob San Francisco, US 27 171

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