Yeast cell capable of simultaneously fermenting hexose and pentose sugars

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11198847
APP PUB NO 20200377846A1
SERIAL NO

16966741

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Abstract

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The invention relates to a method for preparing a yeast which is capable of simultaneously fermenting a pentose and a hexose sugar, the method comprising providing a yeast which comprises: one or more heterologous genes encoding an enzyme of a pentose metabolic pathway, a disruption of a gene encoding a ribulose-phosphate 3-epimerase and a disruption of a gene encoding a glucose-6-phosphate isomerase, and one or more overexpressed endogenous genes encoding an enzyme of the pentose phosphate pathway; and subjecting the yeast to evolutionary engineering on a medium comprising a hexose sugar and at least one pentose sugar, selecting for a yeast with improved growth rate when grown on a media comprising a hexose and at least one pentose sugar, so as to obtain an evolved yeast.

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Patent Owner(s)

Patent OwnerAddress
DSM IP ASSETS B VHET OVERLOON 1 HEERLEN 6411

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Papapetridis, Ioannis Delft, NL 6 8
Pronk, Jacobus Thomas Delft, NL 41 294
Van, Maris Antonius Jeroen Adriaan Stockholm, SE 26 107
Verhoeven, Maarten Dirk Delft, NL 5 5

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