Ultra-stable protein ionic liquids

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United States of America Patent

PATENT NO 11385201
SERIAL NO

16587124

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Abstract

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A method of forming a stable protein complex comprising: providing aqueous protein complexes, wherein the protein complexes are one or more of photosystem I complex from spinach, photosystem II complex from spinach, chlorophyll antennae, thylakoids, bacteriochlorophylls, chlorosomes, and photosystems from green algae, cyanobacteria, and plants; cationizing the aqueous protein complexes by the addition of stoichiometric amounts of a crosslinker in the presence of a coupling reagent; titrating the cationized protein complexes with a counter anionic polymer until the protein cation/anion pair solution becomes negative by zeta potential measurement, to create at least one antibody cation/anion pair in aqueous solution. The protein complexes cation/anion pair solution may be lyophilized to remove all of the water, forming a lyophilized solid. The lyophilized solid may be heated until a protein complex ionic liquid is generated. The cationized protein complexes may be purified from excess coupling reagents by dialysis in water.

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Patent OwnerAddress
UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCEKIRTLAND AFB NM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dennis, Patrick B Cincinnati, US 12 7
Naik, Rajesh R Centerville, US 28 81
Slocik, Joseph M Dayton, US 15 7

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