5′S-LNA nucleotides and oligonucleotides

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United States of America Patent

PATENT NO 11390641
APP PUB NO 20190292213A1
SERIAL NO

16317586

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Abstract

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The invention relates to a compound of formula (I) wherein R2 and R4 are joined and together form a group, such a —CH2O—. The compound of formula (I) can be used in the manufacture of 5′S-LNA oligonucleotides as antisense drugs.

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Patent Owner(s)

Patent OwnerAddress
HOFFMANN-LA ROCHE INC150 CLOVE ROAD OVERLOOK AT GREAT NOTCH STE 8 LITTLE FALLS NJ 07424

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bleicher, Konrad Basel, CH 66 356
Duschmalé, Joerg Basel, CH 8 1
Saha, Goutam Kolkata, IN 11 30
Shaikh, Juber Abdulhamid Hinjewadi MIDC, IN 3 0

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