Method for preparing cangrelor tetrasodium salt

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United States of America Patent

PATENT NO 11440934
APP PUB NO 20210371448A1
SERIAL NO

16768037

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Abstract

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The present application relates to a method for prepare a Cangrelor tetrasodium salt, comprising: using N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)sulfonyl]adenosine as a raw material to undergo two steps of reaction to obtain a reaction solution containing the Cangrelor tetrasodium salt; separating and purifying once by C18 silica gel column chromatography so as to obtain a Cangrelor tetrasodium salt pure product. The present application has the advantages of short synthesis route, mild reaction conditions, sufficient reaction, simple operation, high product yield, high purity, and environmental friendliness, and is suitable for large-scale preparation.

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Patent Owner(s)

Patent OwnerAddress
YABAO PHARMACEUTICAL GROUP CO LTDYUNCHENG SHANXI 044600

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bao, Jiyu Shanxi, CN 1 0
Gao, Junfeng Shanxi, CN 4 5
Tan, Zhouhong Shanxi, CN 1 0
Tang, Fanghui Shanxi, CN 4 7

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