Polynucleotides, reagents, and methods for nucleic acid hybridization

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United States of America Patent

PATENT NO 11492665
SERIAL NO

16417023

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Abstract

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Provided herein are compositions, methods and systems relating to libraries of polynucleotides such that the libraries allow for accurate and efficient hybridization after binding to target sequences. Further provided herein are probes, blockers, additives, buffers, and methods that result in improved hybridization. Such compositions and methods are useful for improvement of Next Generation Sequencing applications, such as reducing off-target binding or reducing workflow times.

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Patent Owner(s)

  • TWIST BIOSCIENCE CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Butcher, Kristin D San Francisco, US 4 89
Chen, Siyuan San Mateo, US 96 2665
Chilton, E Hutson San Francisco, US 3 69
Gantt, Richard San Francisco, US 7 142
Zeitoun, Ramsey Ibrahim San Francisco, US 14 770

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