NIR to SWIR fluorescent compounds for imaging and detection

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United States of America Patent

PATENT NO 11549017
APP PUB NO 20190100654A1
SERIAL NO

16124639

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Abstract

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This disclosure provides a family of compounds that absorb and fluoresce in the short wave infrared region (SWIR, optionally 1000 nm to 1300 nm), including hydrophilic compounds that exhibit absorption and emission spectral profiles in aqueous solutions substantially similar to those observed in organic solvents such as methanol or DMSO. The compounds can be chemically linked to biomolecules including proteins, nucleic acids, and therapeutic small molecules. The compounds are useful for imaging in a variety of medical, biological and diagnostic applications, including SWIR in vivo imaging of regions of interest within a mammal.

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Patent Owner(s)

Patent OwnerAddress
REVVITY HEALTH SCIENCES INC940 WINTER STREET WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Groves, Kevin Arlington, US 18 326
Ho, Guojie Sudbury, US 9 115
Narayanan, Nara Westford, US 10 419

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