Regulation of the RAS/cAMP/PKA signaling pathway in yeasts for obtaining a fermentation product during fermentation

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United States of America Patent

PATENT NO 11667680
APP PUB NO 20190106464A1
SERIAL NO

16085959

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Abstract

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The present disclosure relates to the modulation in the RAS/cAMP/PKA signaling pathway for maintaining the propagation efficiency and increasing fermentation efficiency of yeast cells. The present disclosure provides yeast cells having or engineered to exhibit a modulation in signaling in a RAS/cAMP/PKA pathway, depending on conditions. For example the yeast cells can be selected or genetically modified to express a mutated Ras1 protein, a mutated Ras2 protein, a mutated Ira1 protein and/or a mutated Ira2 protein, optionally in combination with specific promoters. Also provided herewith are methods for propagating the yeast cells as well as using the yeast cells to generate a fermented product (such as ethanol).

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Patent OwnerAddress
DANSTAR FERMENT AGSWISS EXPRESS ZUG ZUG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Argyros, Aaron Etna, US 62 157
Fisher, Janet Norwich, US 11 23
Froehlich, Allan Norwich, US 12 30
Henningsen, Brooks Winchester, US 17 11
Oeser, Michelle Croydon, US 6 4
Rice, Charles F Hopkinton, US 24 74
Zelle, Rintze M East Thetford, US 4 7

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