Methods of detecting cell-free DNA in biological samples

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United States of America Patent

PATENT NO 11781188
SERIAL NO

16500929

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The present disclosure is directed to methods of detecting cell-free DNA (cfDNA) in biological samples and using it to quantify organ damage and identify pathogens. In some aspects, the biological samples are from patients who have undergone solid-organ transplantation. The disclosure is also directed to methods of detecting and analyzing methylation patterns in cell-free DNA from organ transplant patients to identify the presence of pathogens as well as quantify contributing tissue proportions as a measurement of the host response.

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Patent OwnerAddress
CORNELL UNIVERSITY395 PINE TREE ROAD SUITE 310 ITHACA NY 14850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burnham, Philip Smith Ithaca, US 2 0
Cheng, Alexandre Pellan Ithaca, US 4 0
Dadhania, Darshana Ithaca, US 1 0
De, Vlaminck Iwijn Ithaca, US 17 14
Lee, John Richard Ithaca, US 2 0
Suthanthrian, Manikkam Ithaca, US 2 0

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