ASGPR-binding compounds for the degradation of extracellular proteins

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United States of America Patent

PATENT NO 11819551
APP PUB NO 20230097256A1
SERIAL NO

17877538

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Abstract

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Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.

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Patent Owner(s)

Patent OwnerAddress
AVILAR THERAPEUTICS INC400 TOTTEN POND ROAD SUITE 110 WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jesse Jingyang Lexington, US 7 5
Karra, Srinivasa Pembrooke, US 22 93
Ray, Soumya Qunicy, US 25 166
Saulnier, Mark George Higganum, US 10 14
Sprott, Kevin Tyler Needham, US 8 5
Wiles, Jason Allan Madison, US 102 2022

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