Template-directed nucleic acid targeting compounds

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United States of America Patent

PATENT NO 11859242
APP PUB NO 20200340044A1
SERIAL NO

16955593

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Abstract

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Described herein are genetic recognition reagents comprising terminal aromatic moieties that bind specifically to a template nucleic acid and concatenate. Also provided are methods of using the genetic recognition reagents, e.g., to treat or diagnose a repeat expansion disorder, such as DMI.

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Patent Owner(s)

Patent OwnerAddress
CARNEGIE MELLON UNIVERSITY5000 FORBES AVENUE PITTSBURGH PA 15213

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bahal, Raman Glastonbury, US 13 29
Hsieh, Wei-Che New Taipei, TW 26 33
Ly, Danith H Pittsburgh, US 29 111

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