Compositions and methods for regulation of chronic toxoplasma infection

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United States of America Patent

PATENT NO 11945845
APP PUB NO 20220235101A1
SERIAL NO

17595894

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Abstract

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The present disclosure provides genetically altered protozoan parasites comprising a mutation in a bradyzoite formation deficient 1 (BFD1) gene, wherein the mutation inhibits differentiation of the parasite into a bradyzoite. The genetically altered protozoan parasites can be utilized in vaccine compositions and in methods of treating apicomplexan parasite infection.

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Patent Owner(s)

Patent OwnerAddress
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCHNINE CAMBRIDGE CENTER CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lourido, Sebastian Cambridge, US 1 0
Waldman, Ben Cambridge, US 1 0

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