Photodynamic therapy composition

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United States of America Patent

PATENT NO 11975074
APP PUB NO 20210060170A1
SERIAL NO

16901874

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Abstract

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A method of treating a PSMA expressing cancer in a subject includes (a) administering to the subject a PSMA-targeted phthalocyanine conjugate compound having the formula (I), (b) detecting the PSMA-targeted phthalocyanine compound bound to and/or complexed with the prostate cancer cells to determine the location and/or distribution of the prostate cancer cells in the subject, (c) surgical resection of the detected cancer, and (d) irradiating the PSMA-targeted phthalocyanine compound at the site of surgical resection, thereby inducing the cytotoxic effects of the phthalocyanine compound on residual prostate cancer cells following surgical resection.

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Patent Owner(s)

Patent OwnerAddress
CASE WESTERN RESERVE UNIVERSITY2040 ADELBERT ROAD CLEVELAND OHIO 44106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Basilion, James Cleveland, US 24 198

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