Main group metal complex and its preparation method and use

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United States of America Patent

PATENT NO 12018038
APP PUB NO 20210253603A1
SERIAL NO

16973474

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Abstract

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The present invention provides a main group metal complex, or pharmaceutically acceptable salt, solvate, non-covalent bond compound or prodrug thereof, which is composed of planar tetradentate Schiff base ligands and p-block main group metal ions. The main group metal complex can be conveniently prepared, and shows high cytotoxicity to a variety of cancer cell lines and has selective killing effect. The pharmaceutical compositions or pharmaceutical preparations prepared from the main group metal complex according to the present invention can be used for treatment of tumors. The main group metal complex also has fluorescent properties and can be used for fluorescent labeling.

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Patent Owner(s)

Patent OwnerAddress
PEKING UNIVERSITY100871 NO 5 THE SUMMER PALACE ROAD BEIJING HAIDIAN DISTRICT BEIJING CITY BEIJING CITY 100871

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wang, Bingwu Beijing, CN 11 19
Yin, Haoyan Beijing, CN 1 0
Zhang, Junlong Beijing, CN 8 0

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