Methods and kits for preparing radionuclide complexes

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United States of America Patent

PATENT NO 12036293
APP PUB NO 20210138094A1
SERIAL NO

17154926

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Abstract

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A method for preparing a complex comprising a radioisotope of gallium for use in radiotherapy or in a medical imaging procedure, said method comprising adding a gallium radioisotope solution obtained directly from a gallium radionuclide generator to a composition comprising a pharmaceutically acceptable buffer and optionally also a pharmaceutically acceptable basic reagent, in amounts sufficient to increase the pH to a level in the range of 3 to 8, wherein the composition further comprises a chelator that is able to chelate radioactive gallium within said pH range and at moderate temperature, said chelator being optionally linked to a biological targeting agent. Kits and compositions for use in the method are also described and claimed.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blower, Philip London, GB 8 1
Mullen, Gregory Reading, GB 6 0

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