Compositions and methods involving non-natural aptamer libraries

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 12060559
APP PUB NO 20210332360A1
SERIAL NO

15734522

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The disclosure is directed to methods and compositions for screening a library of aptamers for aptamers having a binding affinity to a target molecule. Specifically, non-natural nucleotides can be introduced onto aptamers immobilized on the surface of beads. The non-natural nucleotides can then be subsequently chemically modified to include additional binding agents. For example, copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions can be used to introduce a wide range of binding agents onto non-natural nucleotides on beads.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
CZ BIOHUB SF LLC499 ILLINOIS STREET SAN FRANCISCO CA 94158

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gordon, Chelsea Lyons Stanford, US 1 0
Niu, Jia Stanford, US 14 10
Soh, Hyongsok Tom San Francisco, US 11 181

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Feb 13, 2028
7.5 Year Payment $3600.00 $1800.00 $900.00 Feb 13, 2032
11.5 Year Payment $7400.00 $3700.00 $1850.00 Feb 13, 2036
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00