Antibody library and antibody screening method using same

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United States of America Patent

PATENT NO 12071710
APP PUB NO 20220275360A1
SERIAL NO

17058124

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Abstract

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The present invention relates to a novel antibody library and an antibody-screening method using same. Having a human sequence-derived specific VH or VL scaffold, the antibody library according to the present invention exhibits high thermodynamic stability and enjoys the advantages of allowing high soluble expression as well as reversible folding. In addition, the antibody according to the present invention includes a variety of rationally controlled CDRs so as to exhibit high specificity and high affinity to all antigens and thus can be advantageously used for selecting an adequate candidate antibody against a target antigen.

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Patent Owner(s)

Patent OwnerAddress
MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH93 IHYEON-RO 30BEON-GIL GIHEUNG-GU YONGIN-SI GYEONGGI-DO 16924

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Hye-Ji Gyeonggi-do, KR 5 1
Jang, Shin A Gyeonggi-do, KR 4 0
Kim, Dong-Sik Gyeonggi-do, KR 31 83
Kim, Gil-Jung Gyeonggi-do, KR 4 0
Lee, Mi Jung Gyeonggi-do, KR 15 61
Oh, Mi Young Gyeonggi-do, KR 2 0
Yoon, Ae Rin Gyeonggi-do, KR 3 1

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