Ionizable cationic lipids

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United States of America Patent

PATENT NO 12077725
APP PUB NO 20230126953A1
SERIAL NO

18064565

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Abstract

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The present disclosure provides compounds useful as ionizable cationic lipids. The ionizable cationic lipids are useful for preparing lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids were engineered with improved stability to oxidative degradation while in storage.

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Patent Owner(s)

Patent OwnerAddress
AKAGERA MEDICINES INC5 ESSEX STREET BOXFORD MA 01921

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drummond, Daryl C Lincoln, US 77 799
Hayes, Mark E Mill Valley, US 26 188
Kirpotin, Dmitri B San Francisco, US 52 317

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