Determination of JAK-STAT3 pathway activity using unique combination of target genes
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United States of America Patent
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Oct 22, 2024
Grant Date -
Apr 4, 2019
app pub date -
Sep 27, 2018
filing date -
Oct 2, 2017
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Abstract
A bioinformatics process which provides an improved means to detect a JAK-STAT3 cellular signaling pathway in a subject, such as a human, based on the expression levels of at least three unique target genes of the JAK-STAT3 cellular signaling pathway measured in a sample. The invention includes an apparatus comprising a digital processor configured to perform such a method, a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such a method, and a computer program comprising program code means for causing a digital processing device to perform such a method. Kits are also provided for measuring expression levels of unique sets of JAK-STAT3 cellular signaling pathway target genes.
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