Modeling ribosome dynamics to optimize heterologous protein production

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12176073
APP PUB NO 20200286578A1
SERIAL NO

16744130

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Abstract

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The presently disclosed subject matter provides a free-energy based model of translation elongation to predict and optimize heterologous gene expression. The model and software allow for the prediction and optimization of genes for increased or decreased protein yield and for increased or decreased protein aggregation.

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Patent Owner(s)

Patent OwnerAddress
NORTH CAROLINA STATE UNIVERSITYOFFICE OF RESEARCH COMMERCIALIZATION 1021 MAIN CAMPUS DRIVE 2ND FLOOR RALEIGH NC 27606

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bitzer, Donald L Raleigh, US 8 379
Vu, Scott Khoi Raleigh, US 2 0

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