Method for preparing gadobutrol

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12180237
APP PUB NO 20210317142A1
SERIAL NO

17270268

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Abstract

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The present invention provides a novel method for preparing high-purity gadobutrol or hydrates thereof. The preparation method of the present invention can have an advantage of simplifying a process by forming a gadolinium complex in-situ without purification of a butrol intermediate and omitting a resin purification process unlike a conventional method for synthesizing gadobutrol. In addition, the preparation method of the present invention can be used to produce high-purity gadobutrol or hydrates thereof at a high yield only through the simple process as above, and thus can be useful in mass production.

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Patent Owner(s)

Patent OwnerAddress
ST PHARM CO LTDSIHEUNG-SI GYEONGGI-DO 15086

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Byeon, Changho Ansan-si, KR 1 0
Chang, Sun Ki Gunpo-si, KR 12 7
Jeong, Seongsu Ansan-si, KR 1 0
Kim, Moonsu Ansan-si, KR 6 0
Lee, Junwon Anyang-si, KR 68 1675
Park, Jongmoon Siheung-si, KR 5 4
Woo, Seokhun Yongin-si, KR 1 0
Yoon, Hoejin Ansan-si, KR 1 0

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