Reagents for detection of chimeric antigen receptor cells

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12181475
APP PUB NO 20210373017A1
SERIAL NO

17226202

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Abstract

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The invention is directed to a method for preparing a detection reagent for CAR expressing cells according to general formula (I)

description='In-line Formulae' end='lead'(X-S)m-D  (I)description='In-line Formulae' end='tail'

    wherein D is a detection moiety, S a spacer unit and X a polypeptide comprising 10 to 80 amino acids and a N3 group, which binds to the antigen binding domain of a chimeric antigen receptor of a cell and m=4-200, characterized in reacting p detection moieties D with a spacer S according to general formula (II)

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Patent Owner(s)

Patent OwnerAddress
MILTENYI BIOTEC B V &CO KGBERGISCH GLADBACH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borke, Tina Bergisch Gladbach, DE 2 0
Dose, Christian Kürten, DE 17 56
Fauerbach, Jonathan Rösrath, DE 8 0
Niemöller, Michaela Bergisch Gladbach, DE 1 0
Richter, Anne Cologne, DE 11 56

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