Linked perfusion to continuous-flow stirred-tank reactor cell culture system

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12195712
APP PUB NO 20210317395A1
SERIAL NO

17355325

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Methods of protein production in a linked culture and production bioreactor system are provided. Such methods include a culture bioreactor (N−1 bioreactor) linked to production bioreactor (N bioreactor). More specifically, the methods include (a) culturing cells with a gene that encodes the protein of interest in a continuous perfusion culture bioreactor (N−1 bioreactor); inoculating a continuously stirred tank reactor (CSTR) production bioreactor (N bioreactor) with cells obtained from step (a); and culturing the cells in the CSTR production bioreactor under conditions that allow production of the protein of interest.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
BOEHRINGER INGELHEIM INTERNATIONAL GMBH55216 INGELHEIM AM RHEIN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Coffman, Jonathan Gaithersbury, US 18 37
Gagnon, Matthew Paul Medford, US 6 1
Hiller, Gregory Walter Wakefield, US 17 116

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Jul 14, 2028
7.5 Year Payment $3600.00 $1800.00 $900.00 Jul 14, 2032
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jul 14, 2036
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00