Signaling and antigen-presenting bifunctional receptors (SABR)

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United States of America

PATENT NO 12221465
APP PUB NO 20190201443A1
SERIAL NO

16122562

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Abstract

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Described herein are compositions and methods for signaling and antigen-presenting bifunctional receptors (SABRs) comprising one or more antigen presenting domains; and one or more signal transduction domains, wherein the one or more antigen presenting domains comprise a binding fragment of a major histocompatibility complex (MHC) molecule. Various immunological functions of the SABRs are also described.

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Patent Owner(s)

  • CALIFORNIA INSTITUTE OF TECHNOLOGY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baltimore, David Pasadena, US 90 1786
Bethune, Michael T Pasadena, US 4 22
Joglekar, Alok V Pasadena, US 1 15
Leonard, Michael T Pasadena, US 5 37

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