pH-modulating biodegradable polymer and poly(glycerol sebacate)-augmented cell culture media

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United States of America

PATENT NO 12221618
APP PUB NO 20210371811A1
SERIAL NO

17405168

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Abstract

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A pH-modulating poly(glycerol sebacate) composition includes poly(glycerol sebacate) and at least one pH-modulating agent associated with the poly(glycerol sebacate). A process of making a pH-modulating poly(glycerol sebacate) composition includes forming a poly(glycerol sebacate) by a water-mediated reaction from glycerol and sebacic acid and associating at least one pH-modulating agent with the poly(glycerol sebacate). A process of modulating a pH of a buffered aqueous solution includes placing a pH-modulating poly(glycerol sebacate) composition in a buffered aqueous solution. The pH-modulating agent is released into the buffered aqueous solution during degradation of the poly(glycerol sebacate) to reduce a decrease in pH of the buffered aqueous solution caused by degradation of the poly(glycerol sebacate).

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Patent Owner(s)

  • THE SECANT GROUP, LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gabriele, Peter D Frisco, US 63 233
Ginn, Brian Harleysville, US 19 16
Harris, Jeremy J Doylestown, US 50 399
Lu, Steven Somerville, US 26 43
Nicholson, Charles Brendan Coopersburg, US 24 77

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