Redox-labile fluorescent probes and their surface immobilization methods for the detection of metabolites

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United States of America

PATENT NO 12228568
APP PUB NO 20210278401A1
SERIAL NO

17258427

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Abstract

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Disclosed herein is an analytical method for profiling lactate (or other analyte) production in single cells, via the use of coupled enzyme reactions on surface-grafted resazurin/resorufin molecules is provided. Additionally surface-bound resazurin/resorufin that retains redox indicator activity as well as microfluidic devices comprising such surface-bound resazurin/resorufin indicators are provided.

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Patent Owner(s)

  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Hanjun Seattle, US 2 0
Li, Zhonghan Portland, US 4 0
Wei, Wei Seattle, US 563 3265
Xue, Min Chino Hills, US 13 90

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