Identification of inhibitors of TcpC and TIR NADase activity

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United States of America

PATENT NO 12247246
APP PUB NO 20230272449A1
SERIAL NO

18059838

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Abstract

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The present invention provides compounds useful as inhibitors of TIR NADase activity, compositions thereof, and methods of using the same. The present invention is useful for inhibition of TIR-domain NADase activity and/or treating microbial infection and/or modulating microbial physiology.

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Patent Owner(s)

  • WASHINGTON UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
DiAntonio, Aaron St. Louis, US 9 18
Essuman, Kow St. Louis, US 5 0
Mao, Xianrong St. Louis, US 6 0
Milbrandt, Jeffrey D St. Louis, US 23 155
Sasaki, Yo St. Louis, US 21 150
Summers, Dan St. Louis, US 4 16

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