Compositions and methods for improving sample identification in indexed nucleic acid libraries

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 12247254
APP PUB NO 20210172014A1
SERIAL NO

17181271

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Abstract

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The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by modifying or blocking 5′ and 3′ ends of pooled indexed polynucleotides from multiple samples, with an optional exonuclease treatment, prior to amplification and sequencing.

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Patent Owner(s)

  • ILLUMINA INC.; ILLUMINA CAMBRIDGE LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bevis-Mott, Claire Cambridge, GB 8 37
Khosroheidari, Mahdieh San Diego, US 4 27
Vermaas, Eric Hans San Diego, US 11 66

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