USE OF 13C NUCLEAR MAGNETIC RESONANCE TO DETECT BINDING TO TARGET MOLECULES
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United States of America Patent
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Issued Date -
Jun 21, 2001
app pub date -
Apr 9, 1999
filing date -
Nov 14, 1995
priority date (Note) -
Abandoned
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Abstract
Methods of detecting binding of a putative ligand to a .sup.13C-enriched target molecule, methods of screening for compounds which bind to a .sup.13C-enriched target molecule, methods for calculating the dissociation constant of a ligand compound which binds to a .sup.13C-enriched target molecule, and methods employed in the determination of the specific amino acids in a .sup.13C-enriched target molecule affected by the binding of a ligand, as well as compounds identified by these screening methods, are provided herewith.
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