Use of heat shock proteins to deliver moieties into cells
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United States of America Patent
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N/A
Issued Date -
Jun 28, 2001
app pub date -
Jan 8, 2001
filing date -
Feb 18, 1997
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to a method of delivering a moiety of interest into a cell comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell. The invention also relates to a method of delivering a moiety of interest into a cell capable of taking up a complex comprising the moiety of interest covalently linked to a heat shock protein comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell. Also encompassed by the present invention is a method of delivering a moiety of interest into an antigen presenting cell comprising contacting the cell with a complex comprising the moiety of interest covalently linked to a heat shock protein, under conditions appropriate for entry of the complex into the cell.
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