INFLAMMATORY MEDIATION OBTAINED FROM ATRACTYLODES LANCEA
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United States of America Patent
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Issued Date -
Jul 5, 2001
app pub date -
Mar 19, 1999
filing date -
Mar 19, 1999
priority date (Note) -
Abandoned
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Abstract
The present invention provides a method for inhibiting the activity of cyclooxygenase-2 and other proinflammatory factors in a mammal. The method comprises administering to the mammal a therapeutically effective or prophylactically effective amount of an organic extract of Atractylodes lancea. The inhibitory effect of the organic extract of this invention on cyclooxygenase-2 activity is substantially greater than the inhibitory effect of the organic extract on cyclooxygenase-1 activity. The present invention also provides a method for treating a mammal having, or at risk for developing, a condition which is benefited by the inhibition of cyclooxygenase-2 or other proinflammatory factors. The method comprises administering to the mammal a therapeutically effective or prophylactically effective amount of the organic extract of Atractylodes lancea.
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